Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → Methyl 3-Amino-2(S)-phenylsulfonylaminopropionate hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | (2S)-3-amino-2-(benzenesulfonamido)propanoic Acid | HCID 10752796 | — |
| 생성물 | Methyl 3-Amino-2(S)-phenylsulfonylaminopropionate hydrochloride | HCID 22865877 | — |
반응 단계
To a stirred solution of 2-1b (5.0 g, 21 mmol) in CH3OH (100 mL) at 0° C. was added SOCl2 (7.5 mL, 100 mmol) dropwise. The cooling bath was then removed and the solution stirred at ambient temperature for 20 h. Concentration and trituration with ether gave 2-2 as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05741796 |
| 출처 데이터셋 | uspto-grants-1998_04 |
| ORD ID | ord-04a782cfc20949a4b3ec1877f90ac250 |
| 출처 메모 | uspto-grants-1998_04 |