Sodium Hydroxide → HCID 19365574, compound

HRID 1600062Notes

Reaction equation

HRID 1600062 reaction equation
[C:1]1([C:7]2[S:29][C:10]3[N:11]([CH2:20][C:21]4[C:26]([F:27])=[CH:25][CH:24]=[CH:23][C:22]=4[F:28])[CH:12]=[C:13]([NH:16]C(=O)C)[C:14](=[O:15])[C:9]=3[C:8]=2[CH3:30])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH-].[Na+]>C(O)C>[C:1]1([C:7]2[S:29][C:10]3[N:11]([CH2:20][C:21]4[C:26]([F:27])=[CH:25][CH:24]=[CH:23][C:22]=4[F:28])[CH:12]=[C:13]([NH2:16])[C:14](=[O:15])[C:9]=3[C:8]=2[CH3:30])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 19365599HCID 19365599, compound

Product 1

HCID 19365574HCID 19365574, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The compound obtained in Example 4 was dissolved in ethanol, and to the solution was added an excess amount of an aqueous 2N sodium hydroxide solution. The mixture was subjected to alkali hydrolysis under heating for24 hours to give the titled compound.

Workup

  1. customThe mixture was subjected to alkali hydrolysis
  2. temperatureunder heating for24 hours

Sources & evidence

ORD record
ord-0a26cfd2d8c24f0bac608b27e5ce2c30
Source dataset
uspto-grants-1998_04
Patent number
US05744479

Reaction notes

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