反应详情

温度

95 °C

A mixture of 9.25 g of product from Example 172, 15 ml of water and 1.5 g of DOWEX-50W-X8(100-200 mesh, hydrogen form) is heated at 95° C. for 4 hours. The reaction mixture is cooled to room temperature, filtered and the residue washed with water. The filtrate is treated with toluene and concentrated in vacuo to give 1.1 g of the desired product as a stickyyellow oil.

1. temperatureThe reaction mixture is cooled to room temperature
2. filtrationfiltered
3. washthe residue washed with water
4. additionThe filtrate is treated with toluene
5. concentrationconcentrated in vacuo