HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lawesson's reagent → (S)-5-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]dihydro-2(3H)-furanthione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lawesson's reagent | HCID 87949 | — |
| Reactant | (5S)-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-2-one | HCID 10014094 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | (S)-5-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]dihydro-2(3H)-furanthione | HCID 54118133 | 57.1% |
Reaction Steps
The title compound is prepared by the procedure of Example 353 using 0.868 g of product from Example 359, 10 ml of toluene and 0,763 g of Lawesson's Reagent to give 0.530 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05744465 |
| Source dataset | uspto-grants-1998_04 |
| ORD ID | ord-52c4a70440f1423eb34a8ef9d1027940 |
| Source note | uspto-grants-1998_04 |