Triethylamine → HCID 9891973, compound

Participants

Reaction Steps

4-Fluorobenzenesulphonyl chloride (0.346 g) was added portionwise to a stirred solution of methyl 5-(2-aminoethyl)-3-(3-pyridylmethyl)-1H-indole1-propanoate (0.50 g) and triethylamine (0.33 g) in dichloromethane (5 ml) at room temperature. The mixture was stirred for 30 minutes and then washed with water and dried (MgSO4). The solvent was evaporated and the residue was chromatographed on silica gel using dichloromethane/methanol (50:1) as eluant. The product fractions were combined and evaporated to give the title compound as a gum (0.59 g).

Provenance & Evidence