Methyl iodide → 3-(3-Pentyloxy-1,2,5-thiadiazol-4-yl)-1-methylpyridinium iodide

HRID 1600218Notes

Reaction equation

HRID 1600218 reaction equation
[CH3:1][I:2].[CH2:3]([O:8][C:9]1[C:13]([C:14]2[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=2)=[N:12][S:11][N:10]=1)[CH2:4][CH2:5][CH2:6][CH3:7]>CC(C)=O>[I-:2].[CH2:3]([O:8][C:9]1[C:13]([C:14]2[CH:15]=[N+:16]([CH3:1])[CH:17]=[CH:18][CH:19]=2)=[N:12][S:11][N:10]=1)[CH2:4][CH2:5][CH2:6][CH3:7]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 151801343-(3-Pentyloxy-1,2,5-thiadiazol-4-yl)pyridine

Product 1

HCID 190755023-(3-Pentyloxy-1,2,5-thiadiazol-4-yl)-1-methylpyridinium iodide

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of methyl iodide (0.3 ml, 5 mmol) and 3-(3-pentyloxy-1,2,5-thiadiazol-4-yl)pyridine (620 mg, 2.5 mmol) in acetone (5 ml) was stirred at room temperature for 18 h. The title compound precipitated from the solution and was collected by filtration toyield 0.81 g (84%).

Workup

  1. customThe title compound precipitated from the solution
  2. filtrationwas collected by filtration toyield 0.81 g (84%)

Sources & evidence

ORD record
ord-ea444ed4593f478fb7f84503a897bcff
Source dataset
uspto-grants-1998_04
Patent number
US05744489

Reaction notes

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