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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 160027Generated: November 1, 2026

Hydrochloric Acid → 4-(4-Chloro-2-fluoroanilino)-6-methoxy-7-(2-(4-pyridyloxy)ethoxy)quinazoline

https://huagongshe.com/reaction/160027

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPotassium CationHCID 813—
ReactantWaterHCID 962—
ReactantN-methyl-2-pyrrolidoneHCID 13387—
ReactantCarbonate IonHCID 19660—
Reactant4-(2-Chloroethoxy)pyridineHCID 22624921—
Reactant4-(4-Chloro-2-fluorophenylamino)-7-hydroxy-6-methoxyquinazolineHCID 135513720—
Product4-(4-Chloro-2-fluoroanilino)-6-methoxy-7-(2-(4-pyridyloxy)ethoxy)quinazolineHCID 9824549—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-5bc87e5072514c38a2a8d2b8589725fa
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)