Methyl iodide → HCID 19075341, compound

HRID 1600293Notes

Reaction equation

HRID 1600293 reaction equation
[CH3:1][I:2].[C:3]([NH:6][C:7]1[C:11]([C:12]2[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=2)=[N:10][O:9][N:8]=1)(=[O:5])[CH3:4]>CC(C)=O>[I-:2].[C:3]([NH:6][C:7]1[C:11]([C:12]2[CH:13]=[N+:14]([CH3:1])[CH:15]=[CH:16][CH:17]=2)=[N:10][O:9][N:8]=1)(=[O:5])[CH3:4]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 19075446HCID 19075446, compound

Product 1

HCID 19075341HCID 19075341, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

Methyl iodide (450 μl, 7.2 mmol) was added to a solution of 3-(3-acetylamino-1,2,5-oxadiazol-4-yl)pyridine (490 mg, 2.4 mmol) in acetone. The reaction mixture was stirred at room temperature for 18 h andthe precipitate collected by filtration. Yield: 640 mg (77%).

Workup

  1. filtrationcollected by filtration

Sources & evidence

ORD record
ord-04aa1a0d3cc64a5e8f5cc487001ca96a
Source dataset
uspto-grants-1998_04
Patent number
US05744489

Reaction notes

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