Water → HCID 19598186, compound

HRID 1600328Notes

Reaction equation

HRID 1600328 reaction equation
[C:1]([O:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=1)(=[O:4])[CH:2]=[CH2:3].[CH3:14][Si:15]([CH3:18])([CH3:17])Cl.O>C(C(C)=O)C(C)C>[C:1]([O:5][CH2:6][C:7]1[CH:8]=[CH:9][C:10]([O:13][Si:15]([CH3:18])([CH3:17])[CH3:14])=[CH:11][CH:12]=1)(=[O:4])[CH:2]=[CH2:3]

Participants

5

Reactant 3

HCID 962WaterHCID 6397ChlorotrimethylsilaneHCID 22123752HCID 22123752, compound

Product 1

HCID 19598186HCID 19598186, compoundYield 59.1%

Reagents, catalysts & solvents 1

HCID 7909Methyl Isobutyl KetoneSolvent2×

Conditions

Temperature
-5 °C

Procedure

1500 g of methyl isobutyl ketone and 100 g of 4-hydroxybenzyl acrylate werecharged into a separable flask of the same type as used in Reference Example 1, and cooled to -5° C. while replacing the flask inside gas with a nitrogen gas, and then 67 g of trimethylchlorosilane was dropwise added thereto over one hour, and then stirring was continued for 2 hours. After completion of the reaction, the reaction mixture was washedwith water and methyl isobutyl ketone was distilled off, whereby 83 g of p-trimethylsilyloxybenzyl acrylate of the following chemical formula was obtained (yield: 59%): ##STR10##

Workup

  1. waitwas continued for 2 hours
  2. customAfter completion of the reaction
  3. distillationwas distilled off

Sources & evidence

ORD record
ord-69255d0a30194462a4c23e9b7e773211
Source dataset
uspto-grants-1998_04
Patent number
US05744562

Reaction notes

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