Boron trifluoride etherate → HCID 86752490, compound

Participants

Reaction Steps

36.5 g (257 mmol) of boron trifluoride etherate was added dropwise over 40 minutes to 33.2 g (266 mmol) of 3-quinuclidinone in 100 ml of diethyl ether and 250 ml of n-hexane. The solid which precipitated out was filtered off on a frit after 1 hour and dried to give 50.2 g (98 percent) of 3-quinuclidinone/boron trifluoride adduct in the form of a white powder. NMR data for the product: The spectra were run in d4 -methanol. The reversible addition of a solvent molecule onto the carbonylgroup resulted in the formation of a hemiacetal, whose signals are indicated below. ##EQU2##(Only the multiplicities resulting from direct 1H--13C couplings are indicated.)

Provenance & Evidence