HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Propanediol → 2-Methylbenzeneboronic acid, propanediol cyclic ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Propanediol | HCID 10442 | — |
| Reactant | 2-Methylphenyl boronic acid | HCID 2733267 | — |
| Solvent | Cyclohexane | HCID 8078 | — |
| Product | 2-Methylbenzeneboronic acid, propanediol cyclic ester | HCID 23005365 | — |
Reaction Steps
A mixture of 1.75 g of 2-methyl phenylboronic acid trimer, 30 ml of cyclohexane, and 0.5 ml of 1,3-propanediol is heated under reflux for 6 hours. The mixture is washed with water and extracted with pentane. The organic phases are dried and concentrated under reduced pressure. In this way 1.8 g of desired product is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05744635 |
| Source dataset | uspto-grants-1998_04 |
| ORD ID | ord-1bb9150ea71544549f16feed5c55b373 |
| Source note | uspto-grants-1998_04 |