HCID 19075525, compound → HCID 19612554, compound

HRID 1600462Notes

Reaction equation

HRID 1600462 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][CH:5]=[C:4]([C:8]2[C:9]([O:13][CH2:14][CH2:15][CH2:16]N3CCCC3=O)=[N:10][S:11][N:12]=2)[CH2:3]1.CN1CCC=[C:26]([C:30]2C(OCCN3CCCC3=O)=NSN=2)[CH2:25]1.CN1CCC=C(C2C(OCCN3C(=O)CO[CH-]3)=N[S:54]N=2)C1.CN1CCC=C(C2C(OCCCN3CCCC3)=NSN=2)C1>>[CH3:1][N:2]1[CH2:7][CH2:6][CH:5]=[C:4]([C:8]2[C:9]([O:13][CH2:14][CH2:15][C:16]3[S:54][CH:25]=[CH:26][CH:30]=3)=[N:10][S:11][N:12]=2)[CH2:3]1

Participants

5

Reactant 4

HCID 19075525HCID 19075525, compoundHCID 19080507HCID 19080507, compoundHCID 19612556HCID 19612556, compoundHCID 131719563HCID 131719563, compound

Product 1

HCID 19612554HCID 19612554, compound

Procedure

1,2,5,6-Tetrahydro-1-methyl-3-(3-(2-(3-thienyl)-1-ethoxy)-1,2,5-thiadiazol-4yl)pyrid 1,2,5,6-Tetrahydro-1-methyl-3-(3-(2-thienylmethoxy)-1,2,5-thiadiazol-4yl)pyrid 1,2,5,6-Tetrahydro-1-methyl-3-(3-(3-thienylmethoxy)-1,2,5-thiadiazol-4yl)pyridine; 1,2,5,6-Tetrahydro-1-methyl-3-(3-(3-(2-pyrrolidon-1-yl)-1-propoxy)-1,2,5-thiadiazol -4-yl)pyridine; 1,2,5,6-Tetrahydro-1-methyl-3-(3-(2-(2-pyrrolidon- 1-yl)- 1-ethoxy)- 1,2,5thi adiaz o l-4- y l )p yri din e; 1,2,5,6-Tetrahydro-1-methyl-3-(3-(2-(2-oxazolidon-3-yl)- 1-ethoxy)- 1,2,5thiadiazo l-4- yl )p yri dine; 1,2,5,6-Tetrahydro-1-methyl-3-(3-(3-(1-pyrrolidyl)- 1-propoxy)- 1,2,5-thiadiazol- -yl)pyridine; or a pharmaceutically acceptable salt thereof.

Sources & evidence

ORD record
ord-132d03fc12c845ae87706a963bd1caa5
Source dataset
uspto-grants-1999_11
Patent number
USRE036375

Reaction notes

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