Aminoisobutyric acid → HCID 21829923, compound

Participants

Reaction Steps

Ammonium hydroxide (1.6 g) aqueous solution (40 mL) was added to aminoisobutyric acid (2.1 g). The solution was cooled to 0° C., to which a solution of a-bromophenylacetyl chloride (6 g) in acetonitrile (5 mL) was slowly added dropwise. After the addition was completed, the mixture was warmed to room temperature and stirred overnight. The precipitate was filtered off and washed with water to give 3.4 g of 2-(α-bromophenylacetylamino)isobutyric acid.

Provenance & Evidence