HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18403062, compound → HCID 9926331, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18403062 | HCID 18403062 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 9926331 | HCID 9926331 | 57% |
Reaction Steps
Benzyl[2,4-di(benzyloxycarbonyl)butyl]phosphinic acid (0.5 g, 1.0 mmol) in 20 mL of water containing 120 mg of 10% Pd/C was hydrogenated at 40 psi for 6 hours. Filtration through a Celite pad followed by evaporation on high vacuum gave 0.17 g (57%) of 2-[(benzylhydroxyphosphinyl)methyl]-pentanedioic acid (4, R=CH2Ph) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05977090 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-f7fa8bba768846d8b8a18dbb96ca196a |
| Source note | uspto-grants-1999_11 |