HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → (+/-)-alpha-(1-Naphthylthiomethyl)-3-pyridinepropanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 1-Naphthalenethiol | HCID 68259 | — |
| Reactant | HCID 10877288 | HCID 10877288 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | (+/-)-alpha-(1-Naphthylthiomethyl)-3-pyridinepropanol | HCID 21830653 | 34.5% |
Reaction Steps
Prepared according to the method described in Example 1 from 1-thionaphthol (0.150 g), sodium hydride (0.044 g) and (±)-3-(2-oxiranylethyl)pyridine (0.150 g) in dimethylformamide (3 ml) at room temperature to give the title compound as an oil (0.100 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05977105 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-806323bc691e48b2992ece19e7b38033 |
| Source note | uspto-grants-1999_11 |