HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Naphthol → (+/-)-alpha-(2Naphthyloxymethyl)-3-pyridinepropanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Naphthol | HCID 8663 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 10877288 | HCID 10877288 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | (+/-)-alpha-(2Naphthyloxymethyl)-3-pyridinepropanol | HCID 21830672 | 17% |
Reaction Steps
Prepared according to the method described in Example 5 from 2-naphthol (0.150 g), sodium hydride (0.044 g; 60% dispersion in oil) and (±)-3-(2-oxiranylethyl)pyridine (0.150 g) in dimethylformamide at 100° C. for 30 minutes to give the title compound as a solid (0.050 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05977105 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-4afc97a3c59a49b79a077c9e927afeaa |
| Source note | uspto-grants-1999_11 |