HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 2-(7-(2-Propenyloxy)naphthyloxymethyl)-3-pyridinepropanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 10877288 | HCID 10877288 | — |
| Reactant | 7-(2-Propenyloxy)-2-naphthalenol | HCID 11171638 | — |
| Product | 2-(7-(2-Propenyloxy)naphthyloxymethyl)-3-pyridinepropanol | HCID 86754740 | — |
Reaction Steps
Prepared according to the method described in Example 5 from 2-(2-propenyloxy)-7-hydroxynaphthalene (1.27 g; J. Org. Chem., (1981) 46, 4988), sodium hydride (60% dispersion in oil; 0.25 g) and (±)-3-(2-oxiranylethyl)pyridine (1.0 g) in dimethylformamide (20 ml) at room temperature to yield the title compound as an oil (0.410 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05977105 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-eb7b7c80f81e4debb700d6ebed2b5020 |
| Source note | uspto-grants-1999_11 |