Dimethylformamide → HCID 21830733, compound

Participants

Reaction Steps

Prepared according to the method described in Example 96d) from sodium hydride (60% dispersion in mineral oil, 0.045 g), trans-4-hydroxystilbene (0.219 g) and (±)-3-hydroxy-5-(3-pyridyl)-1-pentyl para-toluenesulfonate (0.250 g) in anhydrous dimethylformamide (5 ml). The crude product was purified by column chromatography over silica eluting with methanol:dichloromethane (1:19) to give the title compound (0.167 g) as a solid which was recrystallised from ethyl acetate:hexane.

Provenance & Evidence