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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1601011Generated: November 2, 2026

Methyl iodide → Quinoline

https://huagongshe.com/reaction/1601011

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantTriethylamineHCID 8471—
ReactantPotassium CarbonateHCID 11430—
ReactantBenzyl iodideHCID 12098—
Reactant1-IodopropaneHCID 33643—
ReactantHCID 178506446HCID 178506446—
ProductQuinolineHCID 7047—

Reaction Steps

To the solution is added one equivalen to a small excess amount of a base, e.g. potassium carbonate, triethylamine, sodium hydrogen, one equivalent to excess amount of halogens alkyl derivative, e.g. methyl iodide, propyl iodide, benzyl iodide, and the mixture is stirred at a temperature of 0° C. to 80° C. to give a quinoline derivative (ivz).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05977132
Source datasetuspto-grants-1999_11
ORD IDord-c4facb2c96494b0bac7adcbe17d752ca
Source noteuspto-grants-1999_11