HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1601049Generated: October 29, 2026
2-Aminobenzimidazole → HCID 67598292, compound
https://huagongshe.com/reaction/1601049
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Aminobenzimidazole | HCID 13624 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 4-((5-(Chloromethyl)-1H-imidazol-1-yl)methyl)benzonitrile hydrochloride | HCID 9795357 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 67598292 | HCID 67598292 | — |
Reaction Steps
The compound described in Example 26, Step 1 [1-(4-cyanobenzyl)-5-(chloromethyl)imidazole hydrochloride] (0.75 mmol, 0.20 g), 2-aminobenzimidazole (0.90 mmol, 0. 12 g) and diisopropylethylamine (2.25 mmol, 0.29 g) were dissolved in acetonitrile and placed in a nitrogen purged sealed tube and warmed at 80° C. for 18 hr. The precipitate was filtered off to yield 1-(4-cyanobenzyl)-5-(2-amino-1-benzimidazolylmethyl)imidazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05977134 |
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| Source dataset | uspto-grants-1999_11 |
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| ORD ID | ord-169408ecd5dc49ac8c703df61b1f0020 |
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| Source note | uspto-grants-1999_11 |
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