HCID 178483014, compound → HCID 178483013, compound

Participants

Reaction Steps

2-[[N-(Benzyloxycarbonyl)-N-methylamino]methyl]4-azabenzimidazole (385.5 mg, 1.30 mmol) was dissolved in MeOH, and 10% Pd/C was added. The mixture was stirred at RT under H2 (balloon pressure) for 4 h, then the catalyst was removed by filtration through a bed of Celite®. The clear, colorless filtrate was evaporated under vacuum to afford the title compound (237.0 mg, 100%): 1H NMR (250 MHz, CDCl3 /CD3OD) δ 2.48 (s, 3H), 4.06 (s, 2H), 5.38 (br s, 1H), 7.15-8.35 (m, 4H).

Provenance & Evidence