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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1601103Generated: October 27, 2026

4-Phenylpiperidinium chloride → (S)-4-Methyl-2-[4-(4-phenyl-piperidin-1-yl)-benzenesulfonylamino]-pentanoic acid

https://huagongshe.com/reaction/1601103

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Phenylpiperidinium chlorideHCID 82509—
Reactant(S)-2-(4-fluoro-benzenesulfonylamino)-4-methyl-pentanoic acidHCID 6933576—
Product(S)-4-Methyl-2-[4-(4-phenyl-piperidin-1-yl)-benzenesulfonylamino]-pentanoic acidHCID 15432847—

Reaction Steps

In a manner similar to Example 3(b), 4-phenyl-piperidine hydrochloride was condensed with (S)-2-(4-fluoro-benzenesulfonylamino)-4-methyl-pentanoic acid to give the title compound, % C,H,N found: 63.96, 6.96, 6.44.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05977141
Source datasetuspto-grants-1999_11
ORD IDord-ecb56b67bc734053874d086c1107e561
Source noteuspto-grants-1999_11