HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Phenylpiperidinium chloride → (S)-3-Phenyl-2-[4-(4-phenyl-piperidin-1-yl)-benzenesulfonylamino]-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Phenylpiperidinium chloride | HCID 82509 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | (S)-2-(4-fluorophenylsulfonamido)-3-phenylpropanoic acid | HCID 6542174 | — |
| Product | (S)-3-Phenyl-2-[4-(4-phenyl-piperidin-1-yl)-benzenesulfonylamino]-propionic acid | HCID 12114674 | — |
Reaction Steps
In a manner similar to Example 3(b), (S)-2-(4-fluoro-benzenesulfonylamino)-3-phenyl-propionic acid, sodium salt and 4-phenyl-piperidine hydrochloride were condensed to give the title compound, mp=167-169° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05977141 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-d4cebf00e9034c75a65e487882e0b007 |
| Source note | uspto-grants-1999_11 |