HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Phenylpiperidine-4-carboxylic acid, compound with toluene-p-sulphonic acid → (R)-1-(3,4,5-Trimethoxybenzoyl)-3-(2-(4-phenyl-4-carboxypiperidin-1-yl)ethyl)-3-(3,4-dichlorophenyl)pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Phenylpiperidine-4-carboxylic acid, compound with toluene-p-sulphonic acid | HCID 19259 | — |
| Reactant | (S)-1-(3,4,5-trimethoxybenzoyl)-3-(3,4-dichlorophenyl)-3-(2-methanesulfonyloxyethyl)pyrrolidine | HCID 10896745 | — |
| Product | (R)-1-(3,4,5-Trimethoxybenzoyl)-3-(2-(4-phenyl-4-carboxypiperidin-1-yl)ethyl)-3-(3,4-dichlorophenyl)pyrrolidine | HCID 53652197 | — |
Reaction Steps
Alternately prepare by a method similar to Example 5.4.1 using (S)-1-(3,4,5-trimethoxybenzoyl)-3-(3,4-dichlorophenyl)-3-(2-methanesulfonyloxyethyl)pyrrolidine and 4-phenylpiperidine-4-carboxylic acid to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05977139 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-fe6be39c3f484f49a07cce785818fd1c |
| Source note | uspto-grants-1999_11 |