HCID 10908531, compound → HCID 10930203, compound

Participants

Reaction Steps

Ethyl 4-[[10-(17H-tetrabenzo[a,c,g,i]fluoren-17-yl)decyl]oxy]benzoate (9) (2.03 g, 3.03 mmol) was charged to an oven-dried flask along with freshly distilled THF (40 mL) and the resultant solution stirred at room temperature under an atmosphere of nitrogen. Diisobutyl aluminum hydride (12.0 mL, 12.00 mmol) was added via syringe and the resulting mixture stirred at room temperature under nitrogen for 2 hours, after which time, TLC analysis showed that all the starting material had been consumed. The reaction was quenched with the addition of HCl (2 M, 40 mL), and the organic products were extracted with ethyl acetate (3×50 mL), washed with saturated Na2CO3 (40 mL) and water (40 mL), and dried over MgSO4. Excess solvent was removed in vacuo to yield 4-[[10-(17H-tetrabenzo[a,c,g,i]fluoren-17-yl)decyl]oxy]-benzenemethanol (1.7765 g, 2.82 mmol, 94%).

Provenance & Evidence