HCID 11814984, compound → Ciprofloxacin

HRID 1601888Notes

Reaction equation

HRID 1601888 reaction equation
[CH:1]1([N:4]2[C:13]3[C:8](=[CH:9][C:10]([F:20])=[C:11]([N:14]4[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]4)[CH:12]=3)[C:7](=[O:21])[C:6]([C:22]([O:24]CC3C=CC(OCCCCCCCCCCC4C5C(=C6C=CC=CC6=C6C=CC=CC6=5)C5C4=C4C=CC=CC4=C4C=CC=CC4=5)=CC=3)=[O:23])=[CH:5]2)[CH2:3][CH2:2]1.C(O)(C(F)(F)F)=O.C(Cl)Cl>>[CH:1]1([N:4]2[C:13]3[C:8](=[CH:9][C:10]([F:20])=[C:11]([N:14]4[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]4)[CH:12]=3)[C:7](=[O:21])[C:6]([C:22]([OH:24])=[O:23])=[CH:5]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 11814984HCID 11814984, compoundHCID 21863450Trifluoroacetic acid methylene chloride

Product 1

HCID 2764Ciprofloxacin

Procedure

The compound obtained in Step (j) may be stirred in a solution of TFA/DCM to afford the title compound.

Sources & evidence

ORD record
ord-4ce549c1c68a4ef8be4e49892f1c37d6
Source dataset
uspto-grants-1999_11
Patent number
US05977400

Reaction notes

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