HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 21200495, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Reactant | HCID 18414381 | HCID 18414381 | — |
| Reactant | HCID 21200523 | HCID 21200523 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 21200495 | HCID 21200495 | 73.2% |
Reaction Steps
This compound is prepared by the procedure described in step B of EXAMPLE 68 from 1.85 g of 4-(N'-methylureido)-4-phenylpiperidine (free base), 0.44 ml of acetic acid and 26 ml of MeOH, and then 2.75 g of the compound obtained in step A of EXAMPLE 68 in 26 ml of MeOH and 0.55 g of sodium cyanoborohydride in 26 ml of MeOH. This gives 2 g of the expected product. M.p.=170-173° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05977359 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-29360d1a3dbe46c9904878adaecb4edb |
| Source note | uspto-grants-1999_11 |