Hydrochloric Acid → HCID 19610222, compound

Participants

Reaction Steps

To a solution of 4,4-diphenyl-6-methoxyhex-5-enenitrile (4.0 g, 14.4 mmol) in diethylether (60 mL) was added HCl (2 mL, 37 %). The reaction mixture was stirred at room temperature for 16 hr and then the solvent was evaporated in vacuo . The residue was dissolved in dichloro- methane and filtered through a plug of silica gel to give the desired aldehyde as an oil (3.78 g, 99%): 1H-NMR (CDCl3, δ): 2.03-2.10 (m, 2H), 2.56- 2.64 (m, 2H), 3.12 (d, J=3 Hz, 2H), 7.14-7.41 (m, 1OH), 9.34 (t, J=3 Hz, 1H). Anal. Calcd for C1 8HI7NO: C, 82.10; H, 6.51; N, 5.32. Found: C, 82.10; H. 7.02; N. 4.78.

Provenance & Evidence