Dimethylformamide diethylacetal → HCID 178492224, compound

Participants

Reaction Steps

A suspension of 5.41 g (23.6 mmol) of 5-amino-4-cyano-3-(4-methoxy-phenylamino)-pyrazole [for preparation see: J. Heterocyclic Chem. 27, 775 (1990)] in 4.8 ml (27.2 mmol) of N,N-dimethylformamide diethyl acetal (97%) and 100 ml of toluene is heated under reflux for 5 hours. The reaction mixture is then cooled to room temperature and filtered and the filter residue is washed with toluene. Recrystallization of the crude product from methanol/water yields the title compound; m.p. 232-234° C. (decomp.).

Provenance & Evidence