HCID 178425529, compound → HCID 178425528, compound

HRID 1602270Notes

Reaction equation

HRID 1602270 reaction equation
[C:1]([C:3]1[C:4]([NH:13][C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([CH3:20])[CH:15]=2)=[N:5][NH:6][C:7]=1[N:8]=[CH:9][N:10](C)C)#[N:2]>C(N)C1C=CC=CC=1>[CH2:20]([NH:2][C:1]1[N:10]=[CH:9][N:8]=[C:7]2[NH:6][N:5]=[C:4]([NH:13][C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([CH3:20])[CH:15]=3)[C:3]=12)[C:16]1[CH:17]=[CH:18][CH:19]=[CH:14][CH:15]=1

Participants

3

Reactant 1

HCID 178425529HCID 178425529, compound

Product 1

HCID 178425528HCID 178425528, compound

Reagents, catalysts & solvents 1

HCID 7504BenzylamineSolvent

Conditions

Temperature
120 °C

Procedure

Under a nitrogen atmosphere, a mixture of 1 g (3.74 mmol) of 4-cyano-5-(dimethylamino-methyleneamino)-3-(3-methyl-phenylamino)-pyrazole and 10 ml of benzylamine is stirred for 4 hours at 120° C. and then concentrated by evaporation under a HV. The crystalline residue is digested in 10 ml of acetonitrile and filtered and the filter residue is recrystallized from 40 ml of acetonitrile, yielding the title compound; m.p. 200-201° C.

Workup

  1. concentrationconcentrated by evaporation under a HV
  2. filtrationfiltered
  3. customthe filter residue is recrystallized from 40 ml of acetonitrile

Sources & evidence

ORD record
ord-31b7fbfdf67647f2a1bcec050702b038
Source dataset
uspto-grants-1999_11
Patent number
US05981533

Reaction notes

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