2-(Bis(methylsulfanyl)methylidene)propanedinitrile → HCID 19610656, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 17.03 g (0.1 mol) of 3,3-bis-methylmercapto-2-cyano-acrylonitrile, 11.34 ml (0.1 mol) of 4-amino-benzylamine (Aldrich) and 60 ml of ethanol is stirred at 50° C. for 2 hours and then concentrated by evaporation in vacuo. Purification of the residue by flash chromatography on silica gel having a particle size of 0.04-0.06 mm using toluene/isopropanol mixtures (49:1, 97:3, 24:1 and 9:1) yields the title compound; m.p. 100-102° C.

Provenance & Evidence