Sodium Hydroxide → HCID 178489642, compound

HRID 1602313Notes

Reaction equation

HRID 1602313 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:9]([C:11]([C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[CH:14]=2)=O)=O)[CH:6]=[CH:7][CH:8]=1.[NH:21]([C:25]1[NH:26][C:27]2[CH:33]=[CH:32][CH:31]=[CH:30][C:28]=2[N:29]=1)[C:22]([NH2:24])=[NH:23].[OH-].[Na+]>CO.O>[N:29]1[C:28]2[CH:30]=[CH:31][CH:32]=[CH:33][C:27]=2[NH:26][C:25]=1[N:21]=[C:22]1[NH:24][C:9]2([C:5]3[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:4]=3)[NH:24][C:22](=[N:21][C:25]3[NH:29][C:28]4[CH:30]=[CH:31][CH:32]=[CH:33][C:27]=4[N:26]=3)[NH:23][C:11]2([C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[CH:14]=2)[NH:23]1

Participants

6

Reactant 3

HCID 14798Sodium HydroxideHCID 1234931,2-Ethanedione, 1,2-bis(3-methoxyphenyl)-HCID 1785125941-(1H-benzimidazol-2-yl)guanidine

Product 1

HCID 178489642HCID 178489642, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

Following the procedure of Example 1, 3,3'-dimethoxybenzil (1.0 g, 3.69 mmol) and 2-guanidinobenzimidazole (540 mg, 3.08 mmol) in methanol (40 mL) was treated with a solution of sodium hydroxide (200 mg, 5 mmol) in 5 mL of water. The title compound was isolated as pale yellow crystals (655 mg, 73% yield). mp: 276-278 ° C. (dec);MS (ESI) m/z 585 [M+H]+.

Sources & evidence

ORD record
ord-af483b70fff34a01b8a3c06ad504894e
Source dataset
uspto-grants-1999_11
Patent number
US05981551

Reaction notes

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