HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 178478009, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1-(2-Chlorophenyl)-2-phenylethane-1,2-dione | HCID 12619978 | — |
| Reactant | 1-(1H-benzimidazol-2-yl)guanidine | HCID 178512594 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178478009 | HCID 178478009 | — |
Reaction Steps
Following the procedure of Example 1, 1-(2-chlorophenyl)-2-phenylethanedione (0.25 g, 1.0 mmol) and 2-guanidinobenzimidazole (0.215 g, 1.2 mmol) in methanol (12 mL) was treated with a solution of sodium hydroxide (48 mg, 1.2 mmol) in 1.2 mL of water. The title compound was isolated as pale yellow crystals (130 mg, 39% yield). MS (ESI) m/z 559 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05981551 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-bceedfd3b2374144ac1b2334ea20598c |
| Source note | uspto-grants-1999_11 |