5-bromo-N-(1-hydroxy-2-methylpropan-2-yl)pyridine-3-sulfonamide → 5-[6-(4-Chloro-phenyl)-8-methyl-imidazo [1,2-a]pyridin-3-ylethynyl]-pyridine-3-sulfonic acid(2-hydroxy-1,1-dimethyl-ethyl)-amide

HRID 160234Notes

Reaction equation

HRID 160234 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([CH3:19])[c:11]3[n:12]([cH:13]2)[c:14]([C:17]#[CH:18])[cH:15][n:16]3)[cH:6][cH:7]1.[OH:20][CH2:21][C:22]([CH3:23])([CH3:24])[NH:25][S:26](=[O:27])(=[O:28])[c:29]1[cH:30][n:31][cH:32][c:33]([Br:35])[cH:34]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([CH3:19])[c:11]3[n:12]([cH:13]2)[c:14]([C:17]#[C:18][c:33]2[cH:32][n:31][cH:30][c:29]([S:26]([NH:25][C:22]([CH2:21][OH:20])([CH3:23])[CH3:24])(=[O:27])=[O:28])[cH:34]2)[cH:15][n:16]3)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 602093435-bromo-N-(1-hydroxy-2-methylpropan-2-yl)pyridine-3-sulfonamideHCID 866080946-(4-Chloro-phenyl)-3-ethynyl-8-methyl-imidazo[1,2-a]pyridine

Product 1

HCID 167352685-[6-(4-Chloro-phenyl)-8-methyl-imidazo [1,2-a]pyridin-3-ylethynyl]-pyridine-3-sulfonic acid(2-hydroxy-1,1-dimethyl-ethyl)-amide

Sources & evidence

ORD record
ord-c5621c47f11b4c5c81d720668932608e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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