HCID 18787416, compound → HCID 18787387, compound

HRID 1602435Notes

Reaction equation

HRID 1602435 reaction equation
C([O:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([C:15]([OH:17])=[O:16])[C:10]=1[CH2:18][CH2:19][CH2:20][C:21]([OH:23])=[O:22])C1C=CC=CC=1>C(O)C.[Pd]>[OH:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([C:15]([OH:17])=[O:16])[C:10]=1[CH2:18][CH2:19][CH2:20][C:21]([OH:23])=[O:22]

Participants

4

Reactant 1

HCID 18787416HCID 18787416, compound

Product 1

HCID 18787387HCID 18787387, compoundYield 110.8%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A solution of 4-[2-benzyloxy-6-carboxy-phenyl]butanoic acid (5 g, 15.9 mmol) in ethanol was hydrogenated at 60 psi for 4 hr over 10% Pd/C (1 g). The mixture was filtered, and the filtrate was concentrated in vacuo to give a white solid (3.95 g, 99%)

Workup

  1. filtrationThe mixture was filtered
  2. concentrationthe filtrate was concentrated in vacuo

Sources & evidence

ORD record
ord-6ec121d0f3a242efbed81463a8f5a10e
Source dataset
uspto-grants-1999_11
Patent number
US05981571

Reaction notes

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