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HRID 1602485作成日:2026年10月25日

Benzylamine → N-(4-[(7-Methoxyheptyl)oxy]butanoyl)-L-isoleucine, ethyl ester

https://huagongshe.com/reaction/1602485

反応式

関与物質

役割名称HCID仕込み量
反応物BenzylamineHCID 7504—
反応物L-Isoleucine, ethyl esterHCID 6602175—
反応物4-[(7-Methoxyheptyl)oxy]butanoyl chlorideHCID 15383030—
反応物12-Methoxydodecanoyl chlorideHCID 19611759—
反応物L-isoleucine ethyl ester trifluoroacetateHCID 88304807—
生成物N-(4-[(7-Methoxyheptyl)oxy]butanoyl)-L-isoleucine, ethyl esterHCID 131721076—

反応手順

The title compound is prepared by the method of Example 14 using L-isoleucine ethyl ester trifluoroacetate [the title product of Example 44] as a reactant instead of benzylamine, and using an equivalent amount of 4-[(7-methoxyheptyl)oxy]butanoyl chloride [the title product of Example 100] instead of 12-methoxy-1-docecanoyl chloride [the title product of Example 11].

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US05981580
出典データセットuspto-grants-1999_11
ORD IDord-9fb6b2fb80544024b0a284c8b612ed60
出典メモuspto-grants-1999_11