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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 160251Generated: October 26, 2026

Chlorotrimethylsilane → 3-Ethoxycarbonylmethyl-2-oxo-piperidine-3-carboxylic acid ethyl ester

https://huagongshe.com/reaction/160251

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorotrimethylsilaneHCID 6397—
ReactantEthyl bromoacetateHCID 7748—
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
Reactant3-Carbethoxy-2-piperidoneHCID 97773—
ReactantDiisopropylamideHCID 5062348—
ReactantButyllithiumHCID 178418339—
Product3-Ethoxycarbonylmethyl-2-oxo-piperidine-3-carboxylic acid ethyl esterHCID 68574804—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-aefcab99c46d4f94a8ad2aa486b060ef
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)