HCID 70084608, compound → HCID 22008782, compound

Participants

Reaction Steps

A solution of 5-2 (19.0 g, 63 mmol), Mg(ClO4)2 (2.8 g, 12.7 mmol), and CH3CN was heated at 50° C. for 2 hr. The cooled solution was diluted with CDCl3 and then washed with 1N HCl, sat. NaHCO3, and brine, dried (MgSO4), and concentrated. Flash chromatography (silica, 75% EtOAc/hexanes→EtOAc) gave 5-3 as a brown solid.

Provenance & Evidence