HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Proline → HCID 54356438, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Proline | HCID 145742 | — |
| Reactant | 3-Pyridinecarboxaldehyde, 2-amino- | HCID 737633 | — |
| Reactant | HCID 54116747 | HCID 54116747 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 54356438 | HCID 54356438 | — |
Reaction Steps
A mixture of 11-9 (220 mg, 0.8619 mmol), 1-4, 2-amino-3-formylpyridine (137 mg, 1.12 mmol) and proline (99 mg, 0.8619 mmol) in absolute ethanol (5 mL) was heated at reflux for 12 h. Following evaporative removal of the solvent, the residue was chromatographed (silica gel, 70:25:5 chloroform/ethyl acetate/MeOH) to give 11-10 as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05981546 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-c72f97bf7b0e4a9ca9cd8f7bbc5fb1aa |
| Source note | uspto-grants-1999_11 |