p-Toluenesulfonic acid → HCID 53984281, compound

Participants

Reaction Steps

A solution of 12-4 (260 mg, 0.6925 mmol), p-TSA (10 mg) and acetone (20 mL) was heated at reflux for 1 hr. NaHCO3 was added to the cooled reaction mixture and then the mixture was concentrated. The residue was diluted with CHCl3 and then washed with brine, dried (MgSO4), and concentrated to afford 12-5 as an oil.

Provenance & Evidence