HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Proline → HCID 53682092, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Proline | HCID 145742 | — |
| Reactant | 3-Pyridinecarboxaldehyde, 2-amino- | HCID 737633 | — |
| Reactant | HCID 53984281 | HCID 53984281 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 53682092 | HCID 53682092 | — |
Reaction Steps
A mixture of 12-5 (230 mg, 0.6940 mmol), 1-4, (2-amino-3-formylpyridine, 110 mg, 0.9022 mmol) and proline (80 mg, 0.6940 mmol) in absolute ethanol (10 mL) was heated at reflux for 18 h. Following evaporative removal of the solvent, the residue was chromatographed (silica gel, 70:28:2 chloroform/ethyl acetate/MeOH) to give 12-6 as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05981546 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-760042c459f043368f01c09dac9e9330 |
| Source note | uspto-grants-1999_11 |