2-Methoxybenzoic acid → HCID 19612265, compound
Reaction equation
[OH:1][C:2]1[CH:17]=[C:16]([O:18][CH3:19])[CH:15]=[CH:14][C:3]=1[C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[O:12][CH3:13])=[O:5].[CH3:20][O:21]C1C=C(OC)C=CC=1C(C1C=CC=CC=1O)=O.COC1C=CC=CC=1C(O)=O.COC1C=C(OC)C=C(OC)C=1.COC1C(OC)=C(OC)C=CC=1C(C1C=CC=CC=1O)=O>>[CH3:20][O:21][C:17]1[C:2]([OH:1])=[C:3]([CH:14]=[CH:15][C:16]=1[O:18][CH3:19])[C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[O:12][CH3:13])=[O:5]Participants
6
Procedure
According to the method of production of 2-hydroxy-4-methoxy-2'-methoxybenzophenone (4a) and 2,4-dimethoxy-2'-hydroxybenzophenone (4b), 2.00 g (13.14 mmol) of 2-methoxybenzoic acid was reacted with 2.19 g (13.04 m mol) of 1,3,5-trimethoxy benzene to give 2.20 g (7.75 mmol) of 3,4-dimethoxy-2-hydroxy-2'-methoxybenzophenone and 2,3,4-trimethoxy-2'-hydroxybenzophenone. Then, described in example 3, 1.35 g (5.92 m mol) of 3,4-dihydroxybenzophenone as pale yellow powder was produced. The physical properties were measured and are listed below.
Sources & evidence
- ORD record
- ord-8995b16ee8194af4a18f14a8f77e16ea
- Source dataset
- uspto-grants-1999_11
- Patent number
- US05981774
Reaction notes
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