Formic Acid → HCID 15840103, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of tributylamine (2.28 ml, 9.6 mmol), palladium diacetate (0.06 g, 0.3 mmol), formic acid (0.29 ml, 7.4 mmol) and methyl 3-iodo-4-[2-[5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl]-1-propenyloxy]benzoate (1.37 g, 2.72 mmol) in acetonitrile (25 ml) is heated at 95° C. for 4 h. The reaction medium is concentrated on a rotary evaporator under vacuum at 40° C. 40 ml of water and 40 ml of ethyl ether are added. After separation of the phases by settling, the organic phase is washed twice with 20 ml of water, dried over magnesium sulphate and concentrated on a rotary evaporator under vacuum at 40° C.

Provenance & Evidence