反应详情

30 g (0.20 mole) DL-methionine amide were agitated with 250 ml methyl formate for two days at room temperature, during which fine, slightly yellow crystals developed. They were filtered off and recrystallized out of a mixture of 150 ml hexane and 160 ml ethanol. After cooling off, filtering, washing and drying, 23 g (55%) Nα -formyl-DL-methionine amide were obtained in the form of colorless crystals with a melting point of 121-122° C.

1. filtrationThey were filtered off
2. customrecrystallized out of a mixture of 150 ml hexane and 160 ml ethanol
3. temperatureAfter cooling off
4. filtrationfiltering
5. washwashing
6. customdrying