Dimethylformamide dimethyl acetal → HCID 54520283, compound

Participants

Reaction Steps

20.0 g (0.074 mole) of the title compound of Step C and 100 mL of N,N-dimethylformamide dimethyl acetal (purchased from Aldrich Chemical Company) were stirred under nitrogen at reflux overnight. The mixture was concentrated, the residue was stirred in water, and filtered. The solid was dissolved in methylene chloride, dried (MgSO4), filtered, and evaporated to dryness to yield 21.54 g of the title compound of Step D as an oil. 1H NMR (CDCl3): δ2.49 (s,3H), 2.56 (s,3H), 3.16 (s,6H), 3.86 (s,2H), 7.34 (s,1H), 7.57 (s,1H).

Provenance & Evidence