HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminopropanol → HCID 19608267, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminopropanol | HCID 5126 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 6-hydroxy-1,3-dioxaindane-5-carboxylic acid | HCID 15884629 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 19608267 | HCID 19608267 | 52% |
Reaction Steps
4,5-Methylenedioxysalicylic acid was activated by carbonyldiimidazole in methylene chloride and combined with 2-amino-1-propanol in essentially an identical manner as for Example 1 above. An acidic quench and subsequent purification by flash chromatography (SiO2) using (1:1) hexane-ethyl acetate gave 2-(2-hydroxy-4,5-methylenedioxybenzamido)-1-propanol as a waxy white solid in 52% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05985871 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-fb22c2c42c1643a1a52bd210831b0b03 |
| Source note | uspto-grants-1999_11 |