HRID1602883

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID15455641

2-Isocyanato-1,1-dimethoxyethane

C5H9NO3

反应SMILES：O=C(c1ccc(Cl)cc1)c1ccc(Cc2c(Cl)cc(NN=Cc3ccccc3)cc2Cl)cc1

HCID70106066

未命名化合物

PRODUCTS

产物

反应SMILES：COC(CNC(=O)N(N=Cc1ccccc1)c1cc(Cl)c(Cc2ccc(C(=O)c3ccc(Cl)cc3)cc2)c(Cl)c1)OC

HCID54161128

未命名化合物

收率 75%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6342

Acetonitrile

C2H3N

PROCEDURE

实验过程

In 15 ml of acetonitrile was suspended 1.00 g of 1-benzylidene-2-{4-[4-(4-chlorobenzoyl)benzyl]-3,5-dichlorophenyl}hydrazine, and 0.40 g of 2,2-dimethoxyethyl isocyanate was added, and then 15 ml of DBU(1,8-diazabicyclo[5.4.0]undec-7-ene) was added. The mixture was reacted at 20 to 25° C. for 1 hour, and precipitated crystals were collected by filtration to give the above-identified compound as colorless crystals (yield: 75%).

WORKUP

后处理

additionwas added
customThe mixture was reacted at 20 to 25° C. for 1 hour
customprecipitated crystals
filtrationwere collected by filtration

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-f616f2027ec748a8b45647a5e846c195
来源数据集: uspto-grants-1999_11
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US05985875
来源说明: uspto-grants-1999_11

反应SMILES

[CH:1](=[N:8][NH:9][C:10]1[CH:15]=[C:14]([Cl:16])[C:13]([CH2:17][C:18]2[CH:23]=[CH:22][C:21]([C:24](=[O:32])[C:25]3[CH:30]=[CH:29][C:28]([Cl:31])=[CH:27][CH:26]=3)=[CH:20][CH:19]=2)=[C:12]([Cl:33])[CH:11]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:34][O:35][CH:36]([O:41][CH3:42])[CH2:37][N:38]=[C:39]=[O:40]>C(#N)C>[CH:1](=[N:8][N:9]([C:10]1[CH:11]=[C:12]([Cl:33])[C:13]([CH2:17][C:18]2[CH:23]=[CH:22][C:21]([C:24](=[O:32])[C:25]3[CH:26]=[CH:27][C:28]([Cl:31])=[CH:29][CH:30]=3)=[CH:20][CH:19]=2)=[C:14]([Cl:16])[CH:15]=1)[C:39]([NH:38][CH2:37][CH:36]([O:41][CH3:42])[O:35][CH3:34])=[O:40])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1