Sodium Hydroxide → HCID 19608479, compound

HRID 1602939Notes

Reaction equation

[CH2:1]([C:5]1[C:14](=[O:15])[C:13]2[C:8](=[CH:9][C:10]([C:16]([O:18]C)=[O:17])=[CH:11][CH:12]=2)[N:7]([CH2:20][C:21]2[CH:26]=[CH:25][C:24]([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=3[C:33]([O:35]C)=[O:34])=[CH:23][CH:22]=2)[CH:6]=1)[CH2:2][CH2:3][CH3:4].[OH-].[Na+]>>[CH2:1]([C:5]1[C:14](=[O:15])[C:13]2[C:8](=[CH:9][C:10]([C:16]([OH:18])=[O:17])=[CH:11][CH:12]=2)[N:7]([CH2:20][C:21]2[CH:22]=[CH:23][C:24]([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=3[C:33]([OH:35])=[O:34])=[CH:25][CH:26]=2)[CH:6]=1)[CH2:2][CH2:3][CH3:4]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 19608493HCID 19608493, compound

Product 1

HCID 19608479HCID 19608479, compoundYield 76.9%

Procedure

Using the procedure of Example 2, 290 mg of the product of Example 9 and 5 ml of a 5N sodium hydroxide solution were reacted to obtain 210 mg of the desired product melting at >260° C.

Workup

customwere reacted

Sources & evidence

ORD record: ord-bea71579d29b4a50aca3d5481866cea5
Source dataset: uspto-grants-1999_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05985894

Reaction notes

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