Trifluoroacetic acid → HCID 54540070, compound

Participants

Reaction Steps

The product of step (ii) (3.37 g) was dissolved in dichloromethane (100 ml) and triethylsilane (1.39 ml) and treated with trifluoroacetic acid (6.23 ml). The mixture was stirred at room temperature for 36 hours. The solvent was evaporated under reduced pressure and the residue azeotroped three times with toluene. The remaining residue was purified by flash chromatography on silica-gel eluting with 15% methanol in ethyl acetate to give 5-(9H-fluoren-9-yl)uridine as white powder (1.09 g).

Provenance & Evidence