反应详情

To a solution of (E) 3-(5,6-dichloro-2-indolyl)-2-propen-1-ol (13.8 g, 57.0 mmol) in Et2O (450 ml), activated MnO2 (35 g) and NaCl (35 g) were added. The reaction mixture was stirred for two days at RT, filtered on a Celite pad, washed with Et2O and dried over MgSO4 to afford (11.5 g, 47.9 mmol, yield 84.1%) of pure title compound.

1. filtrationfiltered on a Celite pad
2. washwashed with Et2O
3. dry with materialdried over MgSO4